Description

Furan, Tetrahydro-3-Iodo-, (3R)- is a high-value, chiral iodinated building block with the CAS registry number 873063-62-8. This compound is essential for introducing stereochemical complexity and iodine functionality into target molecules, enabling advanced synthetic transformations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is critical for bioactivity.
• Asymmetric Synthesis: Serves as a versatile electrophilic iodine source or a chiral template in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to construct complex, enantiomerically pure architectures.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products that contain iodinated tetrahydrofuran moieties, leveraging its pre-installed stereocenter and functional group.
• Material Science Precursor: Potential use as a specialized monomer or precursor for synthesizing functionalized polymers with unique electronic or optical properties.

Basic Information

Product Name	Furan, Tetrahydro-3-Iodo-, (3R)-
CAS No.	873063-62-8
Molecular Formula	C4H7IO
Molecular Weight	198.00 g/mol
Synonyms	(3R)-3-Iodotetrahydrofuran; (R)-3-Iodotetrahydrofuran; (R)-Tetrahydro-3-iodofuran; 3-Iodotetrahydrofuran, (3R)-; Tetrahydro-3-iodofuran, (R)-; (R)-3-Iodooxolane; 873063-62-8; (R)-3-Iodotetrahydrofuran
EINECS	Contact for details

Quality Control

Every batch of (3R)-3-Iodotetrahydrofuran is produced and analyzed under strict quality management protocols to ensure high chiral purity and chemical consistency. Our standard analytical suite includes chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and GC/HPLC for chemical purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to maximize shelf-life stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.