Description

tert-Butyl (2-(6-Amino-1H-Indol-3-Yl)Ethyl)Carbamate is a high-purity, protected indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is essential for research and production in medicinal chemistry, particularly for organizations developing therapeutics targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing the indole scaffold.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Integral to the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) for neurological and oncological applications.
• Peptidomimetics Synthesis: Employed in the design and synthesis of peptide-like molecules where the protected amino group is required for selective reactions.
• Bioconjugation Chemistry: Useful for creating labeled probes or antibody-drug conjugates (ADCs) due to its reactive amine functionality.
• Academic & Institutional R&D: Serves as a standard reagent in university and contract research organization (CRO) laboratories for exploratory chemical biology projects.

Basic Information

Product Name	tert-Butyl (2-(6-Amino-1H-Indol-3-Yl)Ethyl)Carbamate
CAS No.	873055-12-0
Molecular Formula	C15H21N3O2
Molecular Weight	275.35 g/mol
Synonyms	Boc-6-Amino-Tryptamine; 6-Amino-Tryptamine Boc Derivative; tert-Butyl N-[2-(6-Amino-1H-indol-3-yl)ethyl]carbamate; 2-(6-Amino-1H-indol-3-yl)ethyl-carbamic acid tert-butyl ester; 3-[2-[(tert-Butoxycarbonyl)amino]ethyl]-1H-indol-6-amine; Boc-AET; N-Boc-6-amino-tryptamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-(6-Amino-1H-Indol-3-Yl)Ethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.