Description

3-Chloro-5,6,7,8-Tetrahydro-4H-Thieno[2,3-D]Azepine is a high-value, heterocyclic organic compound featuring a fused thiophene and azepine ring system, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique molecular scaffold makes it a versatile building block for constructing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutic areas. This compound is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new drug candidates with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting G-protein-coupled receptors (GPCRs) and other biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Serves as a critical intermediate for process optimization and the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for pharmacological profiling and analytical method development.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science applications.

Basic Information

Product Name	3-Chloro-5,6,7,8-Tetrahydro-4H-Thieno[2,3-D]Azepine
CAS No.	873017-02-8
Molecular Formula	C9H10ClNS
Molecular Weight	199.70 g/mol
Synonyms	3-Chloro-4,5,6,7-tetrahydrothieno[2,3-d]azepine; 3-Chloro-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine; Thieno[2,3-d]azepine, 3-chloro-5,6,7,8-tetrahydro-4H-; 4H-Thieno[2,3-d]azepine, 3-chloro-5,6,7,8-tetrahydro-; 873017-02-8; 3-Chlorothieno[2,3-d]azepine tetrahydro derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6,7,8-Tetrahydro-4H-Thieno[2,3-D]Azepine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.