Description

4,5,7,8-Tetrahydro-6H-Thieno[2,3-D]Azepine-6-Carboxylic Acid, T-Butylester is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing complex molecular libraries in drug discovery and lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Serves in the synthetic route for potential APIs, requiring high purity and strict quality control.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable, cost-effective manufacturing processes for potential new drugs.

Basic Information

Item	Details
Product Name	4,5,7,8-Tetrahydro-6H-Thieno[2,3-D]Azepine-6-Carboxylic Acid, T-Butylester
CAS No.	873016-31-0
Molecular Formula	C13H19NO2S
Molecular Weight	253.36 g/mol
Synonyms	tert-Butyl 4,5,7,8-tetrahydro-6H-thieno[2,3-d]azepine-6-carboxylate; 6H-Thieno[2,3-d]azepine-6-carboxylic acid, 4,5,7,8-tetrahydro-, 1,1-dimethylethyl ester; 4,5,7,8-Tetrahydrothieno[2,3-d]azepine-6-carboxylic acid tert-butyl ester; Thienoazepine tert-butyl ester; CAS 873016-31-0
EINECS	Contact for details

Quality Control

Our production of 4,5,7,8-Tetrahydro-6H-Thieno[2,3-D]Azepine-6-Carboxylic Acid, T-Butylester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.