Description

(1-Thien-2-Yl-3,4-Dihydroisoquinolin-2(1H)-Yl)Acetic Acid is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for constructing complex molecular architectures targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex fused heterocyclic systems due to its unique dihydroisoquinoline and thiophene motifs.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.
• Academic & Industrial R&D: Applied in research exploring new chemical entities and reaction methodologies in synthetic organic chemistry.

Basic Information

Product Name	(1-Thien-2-Yl-3,4-Dihydroisoquinolin-2(1H)-Yl)Acetic Acid
CAS No.	872696-23-6
Molecular Formula	C₁₅H₁₅NO₂S
Molecular Weight	273.35 g/mol
Synonyms	2-[(1-Thiophen-2-yl-3,4-dihydro-2H-isoquinolin-2-yl)]acetic Acid; (1-Thiophen-2-yl-1,2,3,4-tetrahydroisoquinolin-2-yl)acetic Acid; 872696-23-6; TDIQA; 2-(1-(Thiophen-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)acetic Acid; 1-(2-Thienyl)-1,2,3,4-tetrahydro-2-isoquinolineacetic Acid; 2-[(1-Thien-2-yl-3,4-dihydro-2H-isoquinolin-2-yl)]ethanoic Acid
EINECS	Contact for details

Quality Control

Our (1-Thien-2-Yl-3,4-Dihydroisoquinolin-2(1H)-Yl)Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to industry best practices and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.