Description

5H-1-Benzazepin-5-One, 1,2,3,4-Tetrahydro-7-Methyl-8-(Trifluoromethyl)- is a high-value, heterocyclic organic compound featuring a benzazepinone core structure substituted with methyl and trifluoromethyl groups. This compound is significant as a key synthetic intermediate or building block in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• As a pharmaceutical intermediate in the research and synthesis of new chemical entities (NCEs) targeting central nervous system (CNS) disorders.
• Utilized as a key building block for the development of potential therapeutic agents, including kinase inhibitors or receptor modulators.
• Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Serves as a precursor in agrochemical research for the development of novel pesticides or herbicides.
• Used in academic and institutional research exploring novel heterocyclic chemistry and reaction methodologies.
• Applicable in custom synthesis and contract manufacturing for clients requiring specific, high-purity benzazepinone derivatives.

Basic Information

Product Name	5H-1-Benzazepin-5-One, 1,2,3,4-Tetrahydro-7-Methyl-8-(Trifluoromethyl)-
CAS No.	872624-58-3
Molecular Formula	C₁₂H₁₂F₃NO
Molecular Weight	243.23 g/mol
Synonyms	1,2,3,4-Tetrahydro-7-methyl-8-(trifluoromethyl)-5H-1-benzazepin-5-one; 7-Methyl-8-(trifluoromethyl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 8-(Trifluoromethyl)-7-methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one; Tetrahydro-7-methyl-8-(trifluoromethyl)-5H-1-benzazepin-5-one; Benzazepinone derivative 872624-58-3
EINECS	Contact for details

Quality Control

Our 5H-1-Benzazepin-5-One, 1,2,3,4-Tetrahydro-7-Methyl-8-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.