Description

2-(2-(2-Methoxyethoxy)Ethoxy)Ethyl 2-Mercaptoacetate CAS NO 872492-22-3 is a specialized organic compound featuring a polyethylene glycol (PEG) linker and a terminal thioacetate group. This unique bifunctional structure makes it a valuable intermediate for introducing thiol-reactive sites into polymers, surfaces, and biomolecules. It is primarily sought by R&D and production teams in the pharmaceutical, polymer science, and materials chemistry sectors for applications requiring controlled functionalization and conjugation.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs or as a linker for bioconjugation, attaching therapeutic agents to carriers like PEG.
• Polymer Modification: Serves as a chain transfer agent or functional monomer for introducing thiol or disulfide linkages into polymers, enabling cross-linking or responsive material properties.
• Surface Functionalization: Applied to modify the surface of nanoparticles, gold surfaces, or other materials to create thiolated interfaces for subsequent binding or assembly.
• Bioconjugation Reagent: Facilitates the attachment of peptides, proteins, or other biomolecules to various scaffolds via thiol-maleimide or thiol-disulfide exchange chemistry.
• Research & Development: A key building block in organic synthesis for creating novel compounds with tailored solubility and reactivity profiles.
• Adhesive & Sealant Formulations: Can act as a cross-linking agent or adhesion promoter in specialty formulations.

Basic Information

Product Name	2-(2-(2-Methoxyethoxy)Ethoxy)Ethyl 2-Mercaptoacetate
CAS No.	872492-22-3
Molecular Formula	C10H20O5S
Molecular Weight	252.33 g/mol
Synonyms	2-[2-(2-Methoxyethoxy)ethoxy]ethyl 2-sulfanylacetate; 2-Mercaptoacetic Acid 2-[2-(2-Methoxyethoxy)ethoxy]ethyl Ester; Acetic Acid, 2-Mercapto-, 2-[2-(2-Methoxyethoxy)ethoxy]ethyl Ester; PEG3 Methyl Ether Thioacetate; mPEG3-Thioacetate; Thioacetic Acid S-[2-[2-(2-Methoxyethoxy)ethoxy]ethyl] Ester; 2-(2-(2-Methoxyethoxy)ethoxy)ethyl thioacetate
EINECS	Contact for details

Quality Control

Our 2-(2-(2-Methoxyethoxy)Ethoxy)Ethyl 2-Mercaptoacetate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with relevant regulatory frameworks for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.