Description

2-Pyrrolidinethione, 1-[(Butyldimethylsilyl)Methyl]- is a specialized organosilicon compound featuring a protected thiol functionality. This chemical matters as a valuable building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and novel materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring thiol or protected thiol moieties.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the silyl-protected thiol group offers strategic synthetic advantages.
• Ligand Precursor: Serves as a precursor for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed in the synthesis and functionalization of polymers to introduce specific chemical properties or reactive sites.
• Peptide Mimetics & Bioconjugation: Useful in medicinal chemistry for creating peptide analogs and developing bioconjugation linkers.
• Material Science Research: Applied in the development of advanced materials, including surface modifiers and functional coatings.

Basic Information

Product Name	2-Pyrrolidinethione, 1-[(Butyldimethylsilyl)Methyl]-
CAS No.	872415-87-7
Molecular Formula	C10H21NSSi
Molecular Weight	215.43 g/mol
Synonyms	1-[(Butyldimethylsilyl)methyl]-2-pyrrolidinethione; 1-[(Butyldimethylsilyl)methyl]pyrrolidine-2-thione; N-[(Butyldimethylsilyl)methyl]-2-thioxopyrrolidine; Butyldimethylsilylmethyl 2-pyrrolidinethione; BDMSP-thione; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinethione, 1-[(Butyldimethylsethyl)Methyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.