Description

1H-Indazole-7-Carbonitrile,5-Bromo-3-(4-Piperidinyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole-piperidine hybrid structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting complex biological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology and central nervous system (CNS) disorders.
• Kinase Inhibitor Research: Serves as a core scaffold for the development and optimization of potent and selective kinase inhibitors.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to explore new chemical space and improve pharmacological profiles.
• Biochemical Tool Compound: Employed in biochemical assays and high-throughput screening (HTS) to identify and validate new therapeutic targets.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to the needs of biotechnology and pharmaceutical clients.

Basic Information

Product Name	1H-Indazole-7-Carbonitrile,5-Bromo-3-(4-Piperidinyl)-
CAS No.	872350-27-1
Molecular Formula	C13H13BrN4
Molecular Weight	305.18 g/mol
Synonyms	5-Bromo-3-(piperidin-4-yl)-1H-indazole-7-carbonitrile; 5-Bromo-3-piperidin-4-yl-1H-indazole-7-carbonitrile; 872350-27-1; 3-(4-Piperidinyl)-5-bromo-1H-indazole-7-carbonitrile; 5-Bromo-3-(4-piperidyl)-1H-indazole-7-carbonitrile; 1H-Indazole-7-carbonitrile, 5-bromo-3-(4-piperidinyl)-
EINECS	Contact for details

Quality Control

Our 1H-Indazole-7-Carbonitrile,5-Bromo-3-(4-Piperidinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.