Description

6-Benzyloxy-5-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) research.
• API Synthesis: Used as a core scaffold for constructing complex indole-based active pharmaceutical ingredients.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Biochemical Reagent: Employed in research settings to study enzyme inhibition or receptor binding activities associated with the indole pharmacophore.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.

Basic Information

Product Name	6-Benzyloxy-5-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	872030-46-1
Molecular Formula	C17H14FNO3
Molecular Weight	299.30 g/mol
Synonyms	Methyl 6-(benzyloxy)-5-fluoro-1H-indole-2-carboxylate; 5-Fluoro-6-benzyloxyindole-2-carboxylic acid methyl ester; 6-Benzyloxy-5-fluoroindole-2-carboxylic acid methyl ester; 872030-46-1; Methyl 5-fluoro-6-(phenylmethoxy)-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Benzyloxy-5-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.