Description

tert-Butyl 3-Amino-5-(Aminomethyl)-1H-Indazole-1-Carboxylate is a high-purity, protected indazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional amino and aminomethyl groups, which provide versatile handles for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the indazole core's bioactivity.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying protein function and cellular signaling mechanisms.
• Peptidomimetic Chemistry: The protected amine functionalities make it suitable for constructing non-peptide scaffolds that mimic peptide structures.
• Material Science Research: Potential building block for specialty polymers and functional organic materials requiring specific nitrogen-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	tert-Butyl 3-Amino-5-(Aminomethyl)-1H-Indazole-1-Carboxylate
CAS No.	871709-88-5
Molecular Formula	C13H18N4O2
Molecular Weight	262.31 g/mol
Synonyms	1H-Indazole-1-carboxylic acid, 3-amino-5-(aminomethyl)-, 1,1-dimethylethyl ester; 1-Boc-3-amino-5-(aminomethyl)indazole; tert-Butyl 3-amino-5-(aminomethyl)-1H-indazole-1-carboxylate; 3-Amino-5-(aminomethyl)-1H-indazole-1-carboxylic acid tert-butyl ester; Boc-AAI; 871709-88-5; 1,1-Dimethylethyl 3-amino-5-(aminomethyl)-1H-indazole-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-5-(Aminomethyl)-1H-Indazole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.