Description

tert-Butyl 3-Amino-5-Cyano-1H-Indazole-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a strategically functionalized indazole core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Core scaffold in the research and production of protein kinase inhibitors for oncology applications.
• Chemical Biology Probes: Used to create specialized molecular probes for studying enzyme function and cellular signaling processes.
• Agrochemical Research: Intermediate in the development of new active ingredients for crop protection products.
• Material Science: Potential precursor for specialty polymers or organic electronic materials due to its conjugated structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical development pipelines.

Basic Information

Product Name	tert-Butyl 3-Amino-5-Cyano-1H-Indazole-1-Carboxylate
CAS No.	871709-87-4
Molecular Formula	C₁₃H₁₄N₄O₂
Molecular Weight	258.28 g/mol
Synonyms	1H-Indazole-1-carboxylic acid, 3-amino-5-cyano-, 1,1-dimethylethyl ester; 3-Amino-5-cyano-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 3-amino-5-cyanoindazole-1-carboxylate; 1-Boc-3-amino-5-cyanoindazole; Boc-3-Amino-5-cyanoindazole; 871709-87-4; 3-Amino-5-cyano-1H-indazole-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-5-Cyano-1H-Indazole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.