Description

(E)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylidene)Propan-1-Amine is a high-value, advanced pharmaceutical intermediate featuring a pinacol boronate ester group. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. It is an essential building block for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science, enabling the creation of novel carbon-carbon bonds with high efficiency and selectivity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of bioconjugation reagents and molecular probes for target identification.
• Academic & Industrial R&D: A versatile reagent for methodology development and complex molecule synthesis in organic chemistry laboratories.
• Ligand Synthesis: Used to create novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(E)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylidene)Propan-1-Amine
CAS No.	871366-35-7
Molecular Formula	C16H24BNO2
Molecular Weight	273.18 g/mol
Synonyms	(E)-1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene)propan-1-amine; 4-[(E)-Propyliminomethyl]phenylboronic acid pinacol ester; N-[(1E)-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methylene]-1-propanamine; 871366-35-7; (E)-N-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methylene)propan-1-amine
EINECS	Contact for details

Quality Control

Our (E)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylidene)Propan-1-Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.