Description

2-Methyl-5-(Piperidin-1-Ylsulfonyl)Phenylboronic Acid is a specialized boronic acid derivative featuring a piperidine sulfonyl substituent, making it a valuable building block in modern synthetic chemistry. This compound is crucial for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex aryl-aryl linkages.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by constructing specific biphenyl or heterobiaryl scaffolds.
• Material Science: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Enables the efficient introduction of the 2-methyl-5-(piperidin-1-ylsulfonyl)phenyl moiety into larger molecular architectures via palladium-catalyzed cross-coupling.
• Library Synthesis: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for biological screening.

Basic Information

Product Name	2-Methyl-5-(Piperidin-1-Ylsulfonyl)Phenylboronic Acid
CAS No.	871333-00-5
Molecular Formula	C12H18BNO4S
Molecular Weight	283.15 g/mol
Synonyms	[2-Methyl-5-(piperidin-1-ylsulfonyl)phenyl]boronic acid; 2-Methyl-5-(1-piperidinosulfonyl)benzeneboronic acid; (2-Methyl-5-(piperidine-1-sulfonyl)phenyl)boronic acid; Boronic acid, B-[2-methyl-5-(1-piperidinylsulfonyl)phenyl]-; 5-(Piperidin-1-ylsulfonyl)-2-methylphenylboronic acid; 2-Methyl-5-(piperidin-1-ylsulfonyl)benzeneboronic acid; CAS 871333-00-5
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Piperidin-1-Ylsulfonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.