Description

3-Nitro-5-(Pyrrolidin-1-Ylcarbonyl)Benzeneboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a nitro-substituted aromatic ring and a pyrrolidine amide moiety, enabling complex molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its structural complexity for enhanced bioactivity.
• Material Science: Employed in the creation of advanced organic electronic materials and metal-organic frameworks (MOFs) due to its ability to form stable boronate esters.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors for enzyme studies.
• Academic & Contract Research: Serves as a valuable reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Nitro-5-(Pyrrolidin-1-Ylcarbonyl)Benzeneboronic Acid
CAS No.	871332-81-9
Molecular Formula	C11H13BN2O5
Molecular Weight	264.05 g/mol
Synonyms	3-Nitro-5-(pyrrolidine-1-carbonyl)phenylboronic acid; (3-Nitro-5-(pyrrolidine-1-carbonyl)phenyl)boronic acid; 5-(Pyrrolidine-1-carbonyl)-3-nitrobenzeneboronic acid; Boronic acid, B-[3-nitro-5-(1-pyrrolidinylcarbonyl)phenyl]-; 871332-81-9; 3-Nitro-5-(1-pyrrolidinylcarbonyl)benzeneboronic acid; 3-Nitro-5-(pyrrolidin-1-ylcarbonyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Nitro-5-(Pyrrolidin-1-Ylcarbonyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.