Description

3-(Ethylcarbamoyl)-5-Nitrophenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a nitro-substituted aromatic ring and an ethylcarbamoyl moiety, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by providing a versatile scaffold for structural diversification.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, such as boronate ester-based hydrogels or sensors.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation or as a component in the synthesis of activity-based probes (ABPs) and molecular imaging agents.
• Organic Synthesis: A versatile building block for Suzuki-Miyaura cross-coupling reactions to create biaryl structures, which are common motifs in many functional molecules.
• Ligand Development: Potential use in the creation of novel ligands for catalysis or metal-organic frameworks (MOFs) due to its boronic acid and amide functional groups.

Basic Information

Product Name	3-(Ethylcarbamoyl)-5-Nitrophenylboronic Acid
CAS No.	871332-79-5
Molecular Formula	C9H11BN2O5
Molecular Weight	238.01 g/mol
Synonyms	5-Nitro-3-[(ethylamino)carbonyl]benzeneboronic Acid; (3-(Ethylcarbamoyl)-5-nitrophenyl)boronic Acid; 3-Carbamoyl-5-nitrophenylboronic Acid N-ethyl; Boronic acid, B-[3-[(ethylamino)carbonyl]-5-nitrophenyl]-; 871332-79-5; AKOS025310626; BCP30533
EINECS	Contact for details

Quality Control

Our 3-(Ethylcarbamoyl)-5-Nitrophenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.