Description

3-(Pyrrolidin-1-Ylsulfonyl)Phenylboronic Acid is a high-value organoboron building block featuring a unique pyrrolidine sulfonyl substituent. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioactivity of the pyrrolidine sulfonyl moiety.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by introducing the phenylboronic acid group into heterocyclic scaffolds.
• Material Science: Serves as a monomer or functionalization agent in the development of advanced polymers, ligands for catalysts, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid partner for coupling with various aryl/heteroaryl halides to form biaryl and heterobiaryl structures.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical assays.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	3-(Pyrrolidin-1-Ylsulfonyl)Phenylboronic Acid
CAS No.	871329-61-2
Molecular Formula	C10H14BNO4S
Molecular Weight	255.10 g/mol
Synonyms	[3-(1-Pyrrolidinylsulfonyl)phenyl]boronic Acid; 3-(Pyrrolidine-1-sulfonyl)benzeneboronic Acid; (3-(Pyrrolidine-1-sulfonyl)phenyl)boronic Acid; 3-(N-Pyrrolidinosulfonyl)phenylboronic Acid; B-[3-(1-Pyrrolidinylsulfonyl)phenyl]boronic Acid; 3-Pyrrolidin-1-ylsulfonylbenzeneboronic Acid; CAS 871329-61-2
EINECS	Contact for details

Quality Control

Our 3-(Pyrrolidin-1-Ylsulfonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.