Description

(R)-2-((R)-6,7-Dimethoxy-1-(4-(Trifluoromethyl)Phenethyl)-3,4-Dihydroisoquinolin-2(1H)-Yl)-n-Methyl-2-Phenylacetamide is a high-purity, chiral pharmaceutical intermediate of significant interest in modern drug discovery. Its complex molecular architecture, featuring a tetrahydroisoquinoline core and a trifluoromethylphenyl group, makes it a valuable building block for the synthesis of biologically active compounds. This product is primarily targeted at research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the research and development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Chemical Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry programs to construct complex molecules with specific stereochemistry.
• Research & Development (R&D): Serves as a critical reference standard and starting material in academic and industrial R&D laboratories for pharmacological studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of potential Active Pharmaceutical Ingredients (APIs).
• Ligand and Receptor Studies: Utilized in biochemical assays to study interactions with biological targets due to its specific stereochemical configuration.

Basic Information

Product Name	(R)-2-((R)-6,7-Dimethoxy-1-(4-(Trifluoromethyl)Phenethyl)-3,4-Dihydroisoquinolin-2(1H)-Yl)-n-Methyl-2-Phenylacetamide
CAS No.	871224-64-5
Molecular Formula	C30H31F3N2O3
Molecular Weight	524.58 g/mol
Synonyms	(R)-N-Methyl-2-((R)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-phenylacetamide; (R,R)-2-(6,7-Dimethoxy-1-(4-(trifluoromethyl)phenethyl)-1,2,3,4-tetrahydroisoquinolin-2-yl)-N-methyl-2-phenylacetamide; UNII-9C1K7S5A5T; 9C1K7S5A5T; BDBM50388825; AKOS025310991; CTK8G7235; ZINC000004143756
EINECS	Contact for details

Quality Control

Our (R)-2-((R)-6,7-Dimethoxy-1-(4-(Trifluoromethyl)Phenethyl)-3,4-Dihydroisoquinolin-2(1H)-Yl)-n-Methyl-2-Phenylacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.