Description

(S)-3,3'-Bis[4-(1-Naphthalenyl)Phenyl]-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral phosphoric acid derivative, a key member of the BINOL-based organocatalyst family. Its primary value lies in its exceptional ability to act as a highly selective and efficient catalyst for a wide range of asymmetric organic transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in the synthesis of complex molecules. Its well-defined chiral environment makes it indispensable for creating enantiomerically pure intermediates and active ingredients.

Application

• Asymmetric Organocatalysis: Serving as a privileged chiral Brønsted acid catalyst for enantioselective reactions such as Mannich, Friedel-Crafts, and transfer hydrogenation.
• Pharmaceutical Intermediate Synthesis: Enabling the production of single-enantiomer drug candidates and active pharmaceutical ingredients (APIs) with high optical purity.
• Agrochemical Development: Facilitating the asymmetric synthesis of chiral herbicides, fungicides, and pesticides for enhanced efficacy and environmental profile.
• Fine Chemical Manufacturing: Used in the preparation of specialty chemicals, flavors, and fragrances where stereochemistry is critical.
• Academic & Industrial R&D: A vital tool for methodological development in organic chemistry and process optimization in pilot plants.
• Ligand Precursor: Can be utilized as a precursor for developing novel chiral ligands for metal-catalyzed asymmetric reactions.

Basic Information

Product Name	(S)-3,3'-Bis[4-(1-Naphthalenyl)Phenyl]-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	871130-16-4
Molecular Formula	C58H36O4P
Molecular Weight	827.87 g/mol
Synonyms	(S)-3,3'-Bis(4-(naphthalen-1-yl)phenyl)-[1,1'-binaphthalene]-2,2'-diyl hydrogen phosphate; (S)-TRIP; (S)-3,3'-Bis(4-(1-naphthyl)phenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (S)-Phosphoric acid di[1,1'-binaphthalene]-2,2'-diyl 3,3'-bis[4-(1-naphthalenyl)phenyl] ester; Chiral Phosphoric Acid Catalyst (S)-TRIP; (S)-TRIP Acid; (S)-3,3'-Bis(4-(1-Naphthyl)Phenyl)-BINOL Phosphoric Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) are provided, detailing key parameters such as enantiomeric excess (ee) and assay. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if possible to maximize long-term stability. Handle and store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.