Description

2-Piperizinylpyridine-4-Boronic Acid, Pinacol Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), especially those containing piperazine and pyridine motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile coupling partner with aryl/heteroaryl halides to create biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Employed in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and enzyme inhibitors for biological target validation.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries for drug discovery campaigns.

Basic Information

Product Name	2-Piperizinylpyridine-4-Boronic Acid, Pinacol Ester
CAS No.	871125-87-0
Molecular Formula	C15H23BN2O2
Molecular Weight	274.17 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperazin-1-yl)pyridine; 2-(Piperazin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Piperazin-1-ylpyridine-4-boronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine
EINECS	Contact for details

Quality Control

Our 2-Piperizinylpyridine-4-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.