Description

2-Piperidin-4-Yl-1,2,3,4-Tetrahydro-Isoquinoline Dihydrochloride is a high-purity, complex heterocyclic amine salt of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological intermediate and building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery programs targeting neurological and central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic and piperidine-containing molecular architectures.
• Biochemical Research: Utilized in the study of enzyme inhibition and receptor-ligand interactions relevant to neurological pathways.

Basic Information

Product Name	2-Piperidin-4-Yl-1,2,3,4-Tetrahydro-Isoquinoline Dihydrochloride
CAS No.	871113-10-9
Molecular Formula	C₁₄H₂₀N₂·2HCl
Molecular Weight	289.24 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-(4-piperidinyl)isoquinoline dihydrochloride; 2-(Piperidin-4-yl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride; 2-(4-Piperidyl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride; THIQ-Piperidine Dihydrochloride; 871113-10-9; 2-(4-Piperidinyl)-1,2,3,4-tetrahydroisoquinoline 2HCl
EINECS	Contact for details

Quality Control

Our 2-Piperidin-4-Yl-1,2,3,4-Tetrahydro-Isoquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.