Description

7-(Bromomethyl)Thieno[3,2-D]Pyrimidine is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, enabling critical molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thienopyrimidine scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as semiconductors for OLEDs or OFETs.
• Chemical Biology Probe Development: Employed to create tagged or modified molecules for studying biological processes and target engagement.
• Cross-Coupling Reactions: The bromomethyl group is a reactive handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce complex substituents.
• Nucleophilic Substitution: Facilitates the introduction of amine, thiol, or other nucleophile-containing side chains into the core thienopyrimidine structure.

Basic Information

Product Name	7-(Bromomethyl)Thieno[3,2-D]Pyrimidine
CAS No.	871013-27-3
Molecular Formula	C7H5BrN2S
Molecular Weight	229.10 g/mol
Synonyms	7-(Bromomethyl)thieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 7-(bromomethyl)-; 7-Bromomethylthieno[3,2-d]pyrimidine; (7-Bromomethyl)thieno[3,2-d]pyrimidine; 7-(Bromomethyl)-thieno[3,2-d]pyrimidine; Bromomethyl-thienopyrimidine; 7-BMT; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 7-(Bromomethyl)Thieno[3,2-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.