Description

5-[4-(Methylthio)Phenyl]Thiophene-2-Carboxylic Acid is a high-purity, synthetic organic compound featuring a unique thiophene-carboxylic acid core substituted with a methylthiophenyl group. This specific molecular architecture makes it a valuable and versatile building block (synthon) for advanced research and development in pharmaceutical and material science applications. It is primarily sought after by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), organic electronic materials, and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Organic Semiconductor Research: Serves as a core component for developing π-conjugated systems used in organic light-emitting diodes (OLEDs), organic field-effect transistors (OFETs), and photovoltaic materials.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, or plant growth regulators with tailored properties.
• Ligand and Catalyst Development: The carboxylic acid and sulfur-containing moieties make it suitable for designing novel ligands for metal-organic frameworks (MOFs) or homogeneous catalysis.
• Material Science Additive: Investigated for use as a modifier or additive to enhance specific properties of polymers or coatings.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-[4-(Methylthio)Phenyl]Thiophene-2-Carboxylic Acid
CAS No.	870703-97-2
Molecular Formula	C13H10O2S2
Molecular Weight	262.34 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-[4-(methylthio)phenyl]-; 5-(4-Methylsulfanylphenyl)thiophene-2-carboxylic acid; 4'-(Methylthio)-[2,2'-bithiophene]-5-carboxylic acid; [4-(Methylsulfanyl)phenyl]thiophene-2-carboxylic acid; 5-(p-Methylthiophenyl)thiophene-2-carboxylic acid; TTI-0101 (research code); CAS 870703-97-2
EINECS	Contact for details

Quality Control

Our 5-[4-(Methylthio)Phenyl]Thiophene-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements of research and process development. Standard quality verification includes HPLC for assay and purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.