Description

4-Bromo-3,3-Dimethylindolin-2-One is a high-purity, versatile brominated oxindole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring a bromine atom at the 4-position and gem-dimethyl groups, makes it an essential building block for constructing complex heterocyclic frameworks. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides with novel modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or scaffold in the study of protein-ligand interactions and enzyme inhibition.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.
• Dye & Pigment Synthesis: Used as an intermediate for creating specialized indole-based colorants.

Basic Information

Product Name	4-Bromo-3,3-Dimethylindolin-2-One
CAS No.	870552-47-9
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	4-Bromo-3,3-dimethyl-1,3-dihydro-2H-indol-2-one; 4-Bromo-3,3-dimethyloxindole; 3,3-Dimethyl-4-bromooxindole; 4-Bromo-3,3-dimethyl-2-indolinone; 2H-Indol-2-one, 4-bromo-1,3-dihydro-3,3-dimethyl-; 4-Bromo-3,3-dimethylindolinone; 4-Bromo-3,3-dimethyl-2-oxindole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,3-Dimethylindolin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients in regulated development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.