Description

4,6-Difluoroindole-2-Ethyl Carboxylate is a high-purity fluorinated indole derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of complex molecules with enhanced biological activity and metabolic stability for modern drug discovery. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Material Science: Serves as a precursor for specialty polymers and organic electronic materials due to its unique indole-fluorine structure.
• Biochemical Research: Employed as a probe or substrate in enzymatic studies and biochemical pathway analysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	4,6-Difluoroindole-2-Ethyl Carboxylate
CAS No.	870536-93-9
Molecular Formula	C11H9F2NO2
Molecular Weight	225.19 g/mol
Synonyms	Ethyl 4,6-Difluoro-1H-indole-2-carboxylate; 4,6-Difluoro-1H-indole-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-4,6-difluoroindole; 4,6-Difluoroindole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 4,6-difluoro-, ethyl ester; 870536-93-9; 4,6-Difluoro-2-ethoxycarbonylindole
EINECS	Contact for details

Quality Control

Our 4,6-Difluoroindole-2-Ethyl Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.