Description

Boc-7-Chloro-Dl-Tryptophan CAS NO 870481-87-1 is a protected derivative of the non-natural amino acid 7-chloro-DL-tryptophan, featuring a tert-butoxycarbonyl (Boc) group on the amine functionality. This compound is a critical building block in peptide synthesis and medicinal chemistry research, offering enhanced stability and solubility for complex molecular construction. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the development of novel therapeutic peptides and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel peptide-based drugs and bioactive molecules.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to investigate the role of halogenated tryptophan analogs in biological activity.
• Bioconjugation & Probe Development: Useful for creating labeled peptides or conjugates for biochemical assays and diagnostic applications.
• Academic & Institutional Research: Employed in chemical biology and organic chemistry research for studying peptide structure and function.
• Process Development: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	Boc-7-Chloro-Dl-Tryptophan
CAS No.	870481-87-1
Molecular Formula	C₁₆H₁₉ClN₂O₄
Molecular Weight	338.79 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-7-chloro-DL-tryptophan; Boc-7-Cl-DL-Trp-OH; 2-((tert-Butoxycarbonyl)amino)-3-(7-chloro-1H-indol-3-yl)propanoic acid; 7-Chloro-DL-tryptophan, N-Boc derivative; N-Boc-7-chlorotryptophan; (RS)-2-((tert-Butoxycarbonyl)amino)-3-(7-chloro-1H-indol-3-yl)propanoic acid; DL-7-Chlorotryptophan Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-7-Chloro-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Assay	≥95.0% (on anhydrous basis)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.