Description

Propionic Anhydride-D10 is a deuterated analog of propionic anhydride, where ten hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This high isotopic purity compound is critical for applications requiring precise labeling to study reaction mechanisms, metabolic pathways, and material properties without interference from the standard isotope. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require deuterium-labeled building blocks for synthesis, analytical standards, or spectroscopic studies.

Application

• Deuterated NMR Solvent and Reagent: Used as a chemical shift reference or as a deuterium source in NMR spectroscopy to eliminate solvent interference and analyze molecular structures.
• Pharmaceutical Intermediate Synthesis: Serves as a key labeled precursor in the development and production of deuterated active pharmaceutical ingredients (APIs) for drug discovery and metabolic studies.
• Analytical Standard and Reference Material: Employed as an internal standard in mass spectrometry (MS), gas chromatography (GC), and liquid chromatography (LC) for accurate quantitative analysis.
• Organic Synthesis & Mechanistic Studies: Utilized in organic chemistry research to trace reaction pathways, investigate kinetic isotope effects (KIE), and synthesize specifically labeled compounds.
• Polymer and Material Science: Acts as a modifying agent or labeled monomer in the synthesis of deuterated polymers for neutron scattering experiments and advanced material research.
• Agrochemical Research: Used in the development of labeled pesticides, herbicides, or their metabolites to study environmental fate, degradation, and bioaccumulation.

Basic Information

Product Name	Propionic Anhydride-D10
CAS No.	870471-31-1
Molecular Formula	C6D10O3
Molecular Weight	146.20 g/mol
Synonyms	Perdeuteropropionic Anhydride; Propanoic-d5 Anhydride; Deuterated Propionic Anhydride; (CD3CD2CO)2O; Propionic Acid-d5 Anhydride; Bis(perdeuteropropionyl) Oxide; Propionyl-d5 Anhydride
EINECS	Contact for details

Quality Control

Our Propionic Anhydride-D10 is produced under controlled conditions to ensure high chemical and isotopic purity. Each batch undergoes rigorous analytical testing, including NMR, GC-MS, and IR spectroscopy, to verify identity, isotopic enrichment (typically >98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and moisture absorption. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.