Description

1-(4-Trifluoromethylphenyl)-1H-Benzoimidazole is a specialized heterocyclic organic compound featuring a benzimidazole core substituted with a trifluoromethylphenyl group. This structure makes it a valuable pharmaceutical intermediate and key building block in advanced organic synthesis, particularly for developing active molecules with enhanced metabolic stability and bioavailability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) components.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis and coordination chemistry.
• Fluorinated Compound Library: An important member for constructing screening libraries in medicinal chemistry due to the presence of the trifluoromethyl group.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	1-(4-Trifluoromethylphenyl)-1H-Benzoimidazole
CAS No.	870450-93-4
Molecular Formula	C14H9F3N2
Molecular Weight	262.23 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-1H-benzimidazole; 1-(4-Trifluoromethylphenyl)benzimidazole; 1H-Benzimidazole, 1-[4-(trifluoromethyl)phenyl]-; 4-(1H-Benzimidazol-1-yl)benzotrifluoride; Benzimidazole, 1-(4-trifluoromethylphenyl)-; 1-(α,α,α-Trifluoro-p-tolyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethylphenyl)-1H-Benzoimidazole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support cGMP standards for pharmaceutical applications and can provide material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.