Description

1-(3,5-Bistrifluoromethylphenyl)-1H-Benzoimidazole is a specialized heterocyclic organic compound featuring a benzimidazole core substituted with a highly fluorinated phenyl group. This structure is of significant interest in advanced material science and pharmaceutical research due to its unique electronic properties and potential as a key synthetic intermediate. It is primarily sought by R&D chemists and process development scientists working in the fields of organic electronics, agrochemicals, and medicinal chemistry. The compound's trifluoromethyl groups impart enhanced lipophilicity and metabolic stability, making it a valuable building block for creating novel functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the trifluoromethyl groups can improve biological activity and environmental persistence.
• Material Science: Acts as a building block for organic light-emitting diodes (OLEDs), charge-transport materials, and other electronic components due to its electron-deficient aromatic system.
• Ligand in Catalysis: Can be utilized to synthesize N-heterocyclic carbene (NHC) precursors or other ligands for transition metal catalysis in fine chemical synthesis.
• Academic & Industrial R&D: Employed in exploratory chemistry for constructing complex molecular architectures with tailored properties.

Basic Information

Product Name	1-(3,5-Bistrifluoromethylphenyl)-1H-Benzoimidazole
CAS No.	870450-89-8
Molecular Formula	C16H8F6N2
Molecular Weight	342.24 g/mol
Synonyms	1-[3,5-Bis(trifluoromethyl)phenyl]-1H-benzimidazole; 1-(3,5-Bis(trifluoromethyl)phenyl)benzimidazole; 1H-Benzimidazole, 1-[3,5-bis(trifluoromethyl)phenyl]-; 870450-89-8; Benzimidazole, 1-[3,5-bis(trifluoromethyl)phenyl]-; 1-(3,5-Bis(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 1-(3,5-Bistrifluoromethylphenyl)-1H-Benzoimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing results from NMR, HPLC, and other relevant tests. Our quality commitment supports compliance with REACH and other global regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.