Description

4-(2-Fluorophenyl)Pyrrolidin-2-One is a high-purity fluorinated pyrrolidinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with tailored pharmacological properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients.

Application

• As a key pharmaceutical intermediate in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Utilized as a versatile chemical building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Acts as a precursor in the development of agrochemicals, such as herbicides and fungicides with enhanced activity.
• Employed in material science research for creating specialty polymers and advanced organic electronic materials.
• Serves as a reference standard or analytical reagent in quality control laboratories for method development and validation.
• Used in academic and institutional research for studying structure-activity relationships (SAR) and reaction mechanisms.

Basic Information

Product Name	4-(2-Fluorophenyl)Pyrrolidin-2-One
CAS No.	654633-85-9
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	2-(2-Fluorophenyl)-4-pyrrolidinone; 4-(2-Fluorophenyl)-2-pyrrolidinone; 2-Pyrrolidinone, 4-(2-fluorophenyl)-; 4-(o-Fluorophenyl)-2-pyrrolidinone; 4-(2-Fluorophenyl)-2-pyrrolidone; 4-(2-Fluorophenyl)pyrrolidin-2-one; 2-Fluoro-α-(2-oxopyrrolidin-4-yl)benzene
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.