Description

1,3-Bis[3,5-Bis(trifluoromethyl)phenyl]thiourea is a specialized organofluorine compound belonging to the thiourea derivative class. This high-value chemical is prized for its role as a powerful and selective hydrogen-bonding catalyst and anion receptor in advanced synthetic chemistry. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors who require precise molecular recognition and catalytic activity for complex transformations.

Application

• Asymmetric Synthesis Catalyst: A key component in enantioselective reactions, particularly for the activation of carbonyl compounds and imines.
• Anion Binding and Sensing: Utilized in the development of chemosensors and extraction agents for anions like fluoride and carboxylates due to its strong hydrogen-bond donor properties.
• Pharmaceutical Intermediate: Serves as a building block or catalyst in the synthesis of active pharmaceutical ingredients (APIs) requiring chiral induction.
• Organocatalysis Research: A fundamental reagent in academic and industrial R&D for exploring new catalytic methodologies and reaction mechanisms.
• Material Science: Investigated for incorporation into polymers or supramolecular assemblies to impart specific anion-responsive characteristics.

Basic Information

Product Name	1,3-Bis[3,5-Bis(trifluoromethyl)phenyl]thiourea
CAS No.	1060-92-0
Molecular Formula	C₁₇H₈F₁₂N₂S
Molecular Weight	524.31 g/mol
Synonyms	N,N'-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea; 1,3-Bis(3,5-bis(trifluoromethyl)phenyl)-2-thiourea; Schreiner's Catalyst; Schreiner's Thiourea; Thiourea, N,N'-bis[3,5-bis(trifluoromethyl)phenyl]-; Bistriflimide Thiourea Derivative; Hydrogen-Bond Donor Catalyst; BTF-Thiourea
EINECS	Contact for details

Quality Control

Our production of 1,3-Bis[3,5-Bis(trifluoromethyl)phenyl]thiourea adheres to stringent internal quality standards to ensure batch-to-batch consistency and high catalytic performance. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.