Description

4-Ethyl-5-(4-Methylphenyl)Thiophene-2-Carboxylic Acid is a high-value, multi-functional organic building block characterized by its unique thiophene core substituted with ethyl and p-tolyl groups. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific molecular architecture enables precise chemical modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Organic Electronic Materials: Used in the synthesis of conjugated polymers and small molecules for applications in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Functions as a backbone for creating specialized ligands used in transition metal catalysis for asymmetric synthesis.
• Chemical Research & Development: Employed as a versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of specialized dyes and pigments requiring a thiophene-based chromophore.

Basic Information

Product Name	4-Ethyl-5-(4-Methylphenyl)Thiophene-2-Carboxylic Acid
CAS No.	869950-31-2
Molecular Formula	C14H14O2S
Molecular Weight	246.32 g/mol
Synonyms	5-(p-Tolyl)-4-ethylthiophene-2-carboxylic acid; 4-Ethyl-5-(p-tolyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-ethyl-5-(4-methylphenyl)-; 4-Ethyl-5-(4-methylphenyl)-2-thiophenecarboxylic acid; 4-Ethyl-5-(p-methylphenyl)thiophene-2-carboxylic acid; 869950-31-2; 4-Ethyl-5-(4-methylphenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 4-Ethyl-5-(4-Methylphenyl)Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.