Description

4-Bromo-1-Chloro-3-Methylisoquinoline is a high-purity, halogenated isoquinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the construction of complex heterocyclic systems essential for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays and diagnostic development due to its reactive halogen sites.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	4-Bromo-1-Chloro-3-Methylisoquinoline
CAS No.	869898-11-3
Molecular Formula	C10H7BrClN
Molecular Weight	256.53 g/mol
Synonyms	1-Chloro-4-bromo-3-methylisoquinoline; 3-Methyl-4-bromo-1-chloroisoquinoline; 4-Bromo-1-chloro-3-methyl-isoquinoline; Isoquinoline, 4-bromo-1-chloro-3-methyl-; 869898-11-3; 4-Br-1-Cl-3-Me-isoquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Chloro-3-Methylisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.