Description

2-(Bromomethyl)-4-Chloro-1-Methylbenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and chloro substituents on a methylbenzene core, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical discovery, and materials science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactive halogen sites for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling and other catalytic reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Library Construction: Utilized in combinatorial chemistry and high-throughput screening for drug discovery programs.
• Custom Synthesis: Acts as a starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	2-(Bromomethyl)-4-Chloro-1-Methylbenzene
CAS No.	869721-21-1
Molecular Formula	C9H8BrCl
Molecular Weight	219.52 g/mol
Synonyms	4-Chloro-2-(bromomethyl)-1-methylbenzene; 1-Bromomethyl-4-chloro-2-methylbenzene; 2-Bromomethyl-4-chloro-1-methylbenzene; 4-Chloro-α-bromo-o-xylene; 2-Methyl-5-chlorobenzyl bromide; (4-Chloro-2-methylphenyl)methyl bromide; α-Bromo-4-chloro-2-methyltoluene; 869721-21-1
EINECS	Contact for details

Quality Control

Our production of 2-(Bromomethyl)-4-Chloro-1-Methylbenzene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications. Our quality system is designed to support applications requiring high-purity intermediates under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.