Description

5-(1-Chloro-2-Methylpropan-2-Yl)-3-(Thiophen-2-Yl)-1,2,4-Oxadiazole is a specialized heterocyclic organic compound that serves as a high-value synthetic intermediate in advanced chemical research and development. Its unique molecular architecture, featuring both oxadiazole and thiophene rings, makes it a critical building block for creating novel compounds with targeted biological or material properties. This chemical is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Research: Serves as a core scaffold for developing new generation pesticides, herbicides, and fungicides with improved efficacy and environmental profiles.
• Material Science: Used in the research of advanced organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs), due to its conjugated thiophene-oxadiazole system.
• Chemical Biology Probe Development: Employed as a building block to create molecular probes for studying enzyme function or protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific research programs.

Basic Information

Product Name	5-(1-Chloro-2-Methylpropan-2-Yl)-3-(Thiophen-2-Yl)-1,2,4-Oxadiazole
CAS No.	869709-84-2
Molecular Formula	C10H11ClN2OS
Molecular Weight	242.72 g/mol
Synonyms	5-(1-Chloro-2-methylpropan-2-yl)-3-(thiophen-2-yl)-1,2,4-oxadiazole; 3-(Thiophen-2-yl)-5-(1-chloro-2-methylpropan-2-yl)-1,2,4-oxadiazole; 2-(5-(Thiophen-2-yl)-1,2,4-oxadiazol-3-yl)-2-methylpropyl chloride; 869709-84-2; 5-(1-Chloro-2-methyl-2-propyl)-3-(2-thienyl)-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our 5-(1-Chloro-2-Methylpropan-2-Yl)-3-(Thiophen-2-Yl)-1,2,4-Oxadiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.