Description

Fos-Choline-14, Deuterated is a specialized, isotopically labeled analog of a key phospholipid derivative, essential for advanced research applications. This deuterated compound provides critical stability and unique spectral properties for precise analytical and structural studies. It is primarily utilized by researchers in the life sciences, pharmaceutical development, and analytical chemistry sectors who require high-fidelity molecular probes for NMR spectroscopy, mass spectrometry, and membrane biophysics.

Application

• NMR Spectroscopy: Acts as a crucial internal standard or probe for investigating phospholipid membrane dynamics, structure, and interactions in deuterated solvent systems.
• Mass Spectrometry (MS): Serves as a stable isotope-labeled internal standard for the absolute quantification of natural Fos-Choline-14 and related lipids in complex biological matrices via LC-MS/MS.
• Membrane Protein Studies: Used in the preparation of deuterated lipid bilayers and bicelles for stabilizing membrane proteins and facilitating high-resolution structural analysis.
• Metabolic Tracing: Enables tracking of phospholipid synthesis, turnover, and metabolic pathways in biochemical and pharmacological research.
• Pharmaceutical R&D: Supports drug discovery efforts targeting lipid membranes and membrane-associated proteins by providing a non-perturbing, isotopically labeled component.
• Analytical Reference Standard: Provides a certified reference material for method development, validation, and quality control in analytical laboratories.

Basic Information

Product Name	Fos-Choline-14, Deuterated
CAS No.	869638-98-2
Molecular Formula	C19D40NO4P
Molecular Weight	Contact for details
Synonyms	1-Tetradecanoyl-2-hydroxy-sn-glycero-3-phosphocholine-d40; Deuterated Lyso PC 14:0-d40; 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphocholine-d40; LysoFosCholine 14 deuterated; LPC(14:0/0:0)-d40; 1-Myristoyl-2-lyso-sn-glycero-3-phosphocholine-d40; Deuterated Lysophosphatidylcholine 14:0
EINECS	Contact for details

Quality Control

Every batch of Fos-Choline-14, Deuterated is produced and analyzed under strict quality management protocols to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including NMR and MS analysis, to confirm deuterium incorporation and chemical identity. Certificates of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.