Description

2-Bromo-5-(4-Trifluoromethylphenyl)Thiophene is a high-value, multi-functional heterocyclic building block characterized by its brominated thiophene core and electron-withdrawing trifluoromethylphenyl substituent. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecular architectures in pharmaceutical and materials research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for applications in drug discovery and functional material design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the thiophene and trifluoromethyl motifs.
• Organic Electronic Materials: Serves as a fundamental building block for π-conjugated systems in organic semiconductors, OLEDs (Organic Light-Emitting Diodes), and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, facilitating cross-coupling and other transformative reactions.
• Chemical Research & Development: A versatile substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl and heterobiaryl structures.
• Fluorescent Probe and Sensor Fabrication: The unique electronic properties make it suitable for developing fluorescent dyes and molecular sensors.

Basic Information

Product Name	2-Bromo-5-(4-Trifluoromethylphenyl)Thiophene
CAS No.	869540-85-2
Molecular Formula	C11H6BrF3S
Molecular Weight	307.13 g/mol
Synonyms	2-Bromo-5-[4-(trifluoromethyl)phenyl]thiophene; 5-(4-Trifluoromethylphenyl)-2-bromothiophene; 2-Bromo-5-(4-trifluoromethylphenyl)thiophene; 1-Bromo-4-(5-bromothiophen-2-yl)-2-(trifluoromethyl)benzene (alternative); Thiophene, 2-bromo-5-[4-(trifluoromethyl)phenyl]-; 869540-85-2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(4-Trifluoromethylphenyl)Thiophene is manufactured and tested under a strict quality management system. We guarantee high purity and consistency to meet the rigorous demands of research and scale-up processes. Comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.