Description

2H-Pyrrolo[2,3-B]Pyridin-2-One, 5-Amino-1,3-Dihydro- is a high-purity, heterocyclic organic building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for constructing complex molecular architectures, particularly in medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing fused heterocyclic libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection and pest management solutions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialty chemicals and advanced materials.
• Bioconjugation & Probe Development: The amino functional group allows for conjugation, making it useful in developing biochemical probes and diagnostic agents.

Basic Information

Product Name	2H-Pyrrolo[2,3-B]Pyridin-2-One, 5-Amino-1,3-Dihydro-
CAS No.	869371-00-6
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	5-Amino-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 5-Amino-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; 5-Amino-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 869371-00-6; 5-Amino-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 5-Amino-1H,3H-pyrrolo[2,3-b]pyridin-2-one
EINECS	Contact for details

Quality Control

Our 2H-Pyrrolo[2,3-B]Pyridin-2-One, 5-Amino-1,3-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.