Description

Ethyl 8-Methoxy-2-Oxo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its benzo-fused azepine core structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) with benzazepine pharmacophores.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	Ethyl 8-Methoxy-2-Oxo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine-4-Carboxylate
CAS No.	869363-13-3
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	Ethyl 8-methoxy-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-4-carboxylate; 4-Carbethoxy-8-methoxy-2,3,4,5-tetrahydro-1H-2-benzazepin-1-one; 1H-2-Benzazepine-1-one, 4-(ethoxycarbonyl)-2,3,4,5-tetrahydro-8-methoxy-; 8-Methoxy-1-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylic acid ethyl ester; Benzoazepine carboxylate intermediate 869363-13-3
EINECS	Contact for details

Quality Control

Our Ethyl 8-Methoxy-2-Oxo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.