Description

n-Tosyl-4-Chloro-3-Iodo-7-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound matters as a critical intermediate for constructing complex molecular architectures, enabling the synthesis of novel active ingredients. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical industry for drug discovery programs, particularly in developing kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of advanced active ingredients for crop protection products.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Potential building block for organic electronic materials and specialty polymers due to its functionalized heterocyclic core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	n-Tosyl-4-Chloro-3-Iodo-7-Azaindole
CAS No.	869335-20-6
Molecular Formula	C14H10ClIN2O2S
Molecular Weight	432.66 g/mol
Synonyms	4-Chloro-3-iodo-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine; 1-Tosyl-4-chloro-3-iodo-7-azaindole; 4-Chloro-3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 4-chloro-3-iodo-1-[(4-methylphenyl)sulfonyl]-; 869335-20-6; 4-Chloro-3-iodo-1-(p-tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our n-Tosyl-4-Chloro-3-Iodo-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the standards required for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.