Description

Ethyl 4-(1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of novel small molecule therapeutics, particularly kinase inhibitors. It is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers targeting oncology and immunology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors for oncology research.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Serves as a reference standard or a tool compound in enzymatic assays and biological screening.
• Custom Synthesis: Building block for the contract manufacturing of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for developing novel heterocyclic chemistry and pharmacophore models.

Basic Information

Product Name	Ethyl 4-(1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)Piperazine-1-Carboxylate
CAS No.	869072-37-7
Molecular Formula	C14H18N6O2
Molecular Weight	302.33 g/mol
Synonyms	Ethyl 4-(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazine-1-carboxylate; 1-Piperazinecarboxylic acid, 4-(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-, ethyl ester; Ethyl 4-(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazinecarboxylate; 869072-37-7; 1-Methyl-4-(piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine ethyl carboxylate; UNII-9J8F9K2A4M; 9J8F9K2A4M
EINECS	Contact for details

Quality Control

Our Ethyl 4-(1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.