Description

tert-Butyl 6-Chloro-3-Iodo-1H-Indole-1-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of halogen substituents, which enable precise downstream functionalization for creating complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated indole core.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and proteomics research due to its reactive iodine atom.
• Academic & Contract Research: A versatile scaffold for methodological development in cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis: Provides a protected, reactive starting point for contract manufacturing organizations (CMOs) to produce bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 6-Chloro-3-Iodo-1H-Indole-1-Carboxylate
CAS No.	868694-20-6
Molecular Formula	C13H13ClINO2
Molecular Weight	377.61 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 6-chloro-3-iodo-, 1,1-dimethylethyl ester; 6-Chloro-3-iodo-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 6-chloro-3-iodoindole-1-carboxylate; Boc-6-Cl-3-I-indole; 1-Boc-6-chloro-3-iodoindole; 6-Cl-3-I-1-Boc-indole; 868694-20-6
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 6-Chloro-3-Iodo-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure compliance with exacting purity and identity specifications typical for advanced pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply chain transparency and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.