Description

2H-Indazole-5-Methanamine, 4,5,6,7-Tetrahydro-, (-)- is a high-purity, chiral indazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and chiral building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in creating targeted therapeutics, particularly in neurological and oncological research.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Neurological Research: Used in the development of ligands and modulators for central nervous system (CNS) receptors.
• Oncology Drug Discovery: Serves as a scaffold for creating potential kinase inhibitors and other targeted cancer therapies.
• Asymmetric Synthesis: Employed as a chiral amine building block in the construction of complex, stereochemically defined molecules.
• Chemical Biology: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein interactions.
• Agrochemical Research: Potential intermediate for developing new, selective crop protection agents with specific modes of action.

Basic Information

Product Name	2H-Indazole-5-Methanamine, 4,5,6,7-Tetrahydro-, (-)-
CAS No.	867023-69-6
Molecular Formula	C8H13N3
Molecular Weight	151.21 g/mol
Synonyms	(-)-4,5,6,7-Tetrahydro-2H-indazol-5-ylmethanamine; (5S)-4,5,6,7-Tetrahydro-2H-indazol-5-ylmethanamine; (S)-(-)-4,5,6,7-Tetrahydro-2H-indazol-5-ylmethanamine; 5-Aminomethyl-4,5,6,7-tetrahydro-2H-indazole; (S)-5-Aminomethyl-4,5,6,7-tetrahydro-2H-indazole; (S)-Tetrahydroindazole-5-methanamine; L-867023-69-6
EINECS	Contact for details

Quality Control

Our production of 2H-Indazole-5-Methanamine, 4,5,6,7-Tetrahydro-, (-)- adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, chiral chromatography, NMR, and mass spectrometry to ensure identity, purity, and enantiomeric excess. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.