Description

Ethyl 2-(Cyclopropylamino)-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate is a high-value, multi-functional heterocyclic building block featuring a cyclopropylamino and a trifluoromethyl group on a thiazole core. This compound matters for its role as a critical synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique steric and electronic properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a versatile scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Chemical Biology Probe: Used in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Material Science Applications: Potential building block for advanced organic electronic materials or liquid crystals due to its rigid, conjugated structure and fluorine content.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale cGMP batches.

Basic Information

Product Name	Ethyl 2-(Cyclopropylamino)-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate
CAS No.	866769-74-6
Molecular Formula	C10H11F3N2O2S
Molecular Weight	280.27 g/mol
Synonyms	Ethyl 2-(cyclopropylamino)-4-(trifluoromethyl)thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-(cyclopropylamino)-4-(trifluoromethyl)-, ethyl ester; 2-Cyclopropylamino-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester; Ethyl 2-amino-4-(trifluoromethyl)thiazole-5-carboxylate cyclopropyl derivative; 866769-74-6; CPAT; Cyclopropylamino-trifluoromethyl-thiazole ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(Cyclopropylamino)-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and development applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and related substances are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.