Description

7-Iodo-2,3-Dihydro-Isoindol-1-One is a high-value halogenated isoindolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring an iodine atom on the aromatic ring, makes it a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams working on targeted therapies, including kinase inhibitors and other bioactive small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for oncology and CNS-targeted drugs.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular pathways.
• Agrochemical Synthesis: Serves as a building block for creating new crop protection agents and herbicides.
• Material Science: Potential intermediate for the synthesis of specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	7-Iodo-2,3-Dihydro-Isoindol-1-One
CAS No.	866766-96-3
Molecular Formula	C8H6INO
Molecular Weight	259.05 g/mol
Synonyms	7-Iodoisoindolin-1-one; 1H-Isoindol-1-one, 2,3-dihydro-7-iodo-; 7-Iodo-1-isoindolinone; 866766-96-3; 7-Iodo-2,3-dihydro-1H-isoindol-1-one; 7-Iodoisoindolinone; 7-Iodo-1-oxoisoindoline
EINECS	Contact for details

Quality Control

We supply 7-Iodo-2,3-Dihydro-Isoindol-1-One in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We adhere to strict quality management protocols to ensure batch-to-batch consistency and supply reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.