Description

1H-Indole-1,5-Dicarboxylic Acid, 1,5-Bis(1,1-Dimethylethyl) Ester is a high-purity, synthetically valuable indole derivative, specifically engineered as a protected intermediate for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex chemical processes. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and specialty materials where its unique indole scaffold and tert-butyl ester protecting groups offer strategic advantages in multi-step syntheses.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides that leverage the indole structure for biological activity.
• Organic Synthesis: Serves as a versatile, protected precursor for constructing complex heterocyclic compounds and natural product analogs.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1H-Indole-1,5-Dicarboxylic Acid, 1,5-Bis(1,1-Dimethylethyl) Ester
CAS No.	866587-85-1
Molecular Formula	C20H27NO4
Molecular Weight	345.43 g/mol
Synonyms	Di-tert-butyl 1H-indole-1,5-dicarboxylate; 1,5-Bis(tert-butoxycarbonyl)-1H-indole; 1H-Indole-1,5-dicarboxylic acid bis(1,1-dimethylethyl) ester; 1,5-Di-Boc-indole; tert-Butyl 1,5-indoledicarboxylate; 1,5-Di-tert-butoxycarbonylindole; 1,5-Boc2-indole; 1,5-Indoledicarboxylic Acid Di-tert-butyl Ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1,5-Dicarboxylic Acid, 1,5-Bis(1,1-Dimethylethyl) Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single impurity	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.