Description

1-(5-Bromo-7-Azaindole)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct azaindole scaffold and bromo-substitution. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its modifiable functional groups.
• Chemical Biology Probes: Serves as a core structure for developing selective chemical probes to study enzyme function and cellular signaling processes.
• Agrochemical Research: Employed in the discovery and development of new active ingredients with potential herbicidal or fungicidal properties.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	1-(5-Bromo-7-Azaindole)Ethanone
CAS No.	866545-96-2
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	1-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-7-yl)ethanone; 5-Bromo-7-acetyl-7-azaindole; 1-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-7-yl)ethan-1-one; 5-Bromo-7-acetyl-1H-pyrrolo[2,3-b]pyridine; 7-Acetyl-5-bromo-1H-pyrrolo[2,3-b]pyridine; Ethanone, 1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-7-yl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-7-Azaindole)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.