Description

2-Ethyl-5-(Trifluoromethyl)-2,4-Dihydro-3H-Pyrazol-3-One is a specialized heterocyclic compound featuring a pyrazolone core substituted with ethyl and trifluoromethyl groups. This structure is highly valued for its role as a critical pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical industries to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazolone scaffold.
• Organic Synthesis Building Block: Used in research to construct more complex heterocyclic compounds and fluorinated molecules.
• Material Science Research: Potential precursor for specialty chemicals and functional materials due to its unique fluorinated structure.
• Contract Manufacturing (CMO): Supplied to custom synthesis and contract manufacturing organizations for scale-up and production.

Basic Information

Product Name	2-Ethyl-5-(Trifluoromethyl)-2,4-Dihydro-3H-Pyrazol-3-One
CAS No.	866472-53-9
Molecular Formula	C6H7F3N2O
Molecular Weight	180.13 g/mol
Synonyms	5-(Trifluoromethyl)-2-ethyl-2,4-dihydro-3H-pyrazol-3-one; 2-Ethyl-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one; 3H-Pyrazol-3-one, 2-ethyl-5-(trifluoromethyl)-2,4-dihydro-; 2-Ethyl-5-trifluoromethyl-2,4-dihydro-3H-pyrazol-3-one; ETFP; Pyrazolone derivative 866472-53-9
EINECS	Contact for details

Quality Control

Our 2-Ethyl-5-(Trifluoromethyl)-2,4-Dihydro-3H-Pyrazol-3-One is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.