Description

Ethyl 2-(3,4-Dihydro-1H-Pyrido[4,3-B]Indol-5(2H)-Yl)Acetate Hydrochloride is a high-purity, complex heterocyclic compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research. This product is essential for B2B clients in pharmaceutical R&D, contract manufacturing organizations (CMOs), and fine chemical suppliers focused on advanced drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially in neurological and psychiatric therapeutic areas.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CMOs and CDMOs for the cGMP production of investigational new drugs (INDs) and new drug applications (NDAs).
• Academic Research: Utilized in university and institutional labs for pharmacological studies and the development of new synthetic methodologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	Ethyl 2-(3,4-Dihydro-1H-Pyrido[4,3-B]Indol-5(2H)-Yl)Acetate Hydrochloride
CAS No.	866459-01-0
Molecular Formula	C₁₇H₂₁ClN₂O₂
Molecular Weight	320.81 g/mol
Synonyms	Ethyl 2-(1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetate hydrochloride; 5(2H)-Isoquinolinone, 1,2,3,4-tetrahydro-2-[2-(ethoxycarbonyl)ethyl]-, hydrochloride (9CI); Tetrahydro-β-carboline derivative; Pyridoindole derivative; 866459-01-0; UNII-8VZU8B8WQ5
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3,4-Dihydro-1H-Pyrido[4,3-B]Indol-5(2H)-Yl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.