Description

5‐Bromo‐3,3‐Dimethyl‐2,3‐Dihydro‐1H‐Indole Hydrochloride is a high-purity, synthetically valuable indole derivative used as a key building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Acts as a building block for creating novel pesticides and herbicides with specific biological activity.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized indole motifs.
• Chemical Reference Standard: Supplied as a certified standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	5‐Bromo‐3,3‐Dimethyl‐2,3‐Dihydro‐1H‐Indole Hydrochloride
CAS No.	866364-71-8
Molecular Formula	C10H13BrClN
Molecular Weight	262.57 g/mol
Synonyms	5-Bromo-3,3-dimethylindoline hydrochloride; 5-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole HCl; 1H-Indole, 5-bromo-3,3-dihydro-2,3-dimethyl-, hydrochloride; 3,3-Dimethyl-5-bromoindoline hydrochloride; 5-Bromo-3,3-dimethylindolinium chloride
EINECS	Contact for details

Quality Control

Our 5‐Bromo‐3,3‐Dimethyl‐2,3‐Dihydro‐1H‐Indole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.